Genome Enhancer (first launched as Fly Enhancer in 2001) searches GenBank-formatted genomes for clusters of short nucleotide sequences, such as transcription factor binding sites and microRNA target sequences. You can specify up to ten different sequences and the program will search the entire genome or a selected chromosome arm for clusters of your sequences. You define cluster parameters by specifying how many occurrences of your sequences constitute a cluster, and within how tight a window they must occur to be considered a cluster. The resulting matches are then shown together with information about nearby genes. For more sophisticated searches, you can provide a Boolean condition to indicate how many of each kind of sequence you want in your cluster.
The predecessor of Genome Enhancer, known as Fly Enhancer, has been offered as a free service to the public since 18 December 2001. Plant Enhancer and Worm Enhancer have been offered as free services to the public since 9 March 2002. These were combined into a single site, with the addition of Mosquito Enhancer, on 10 October 2006.
Genome Enhancer is intended for non-commercial use only.
If you wish to use this site for commercial purposes,
please contact Michele Markstein at mmarkstein
opengenomics
org.
To use Genome Enhancer, select an organism on the left.
This website is brought to you by Open Genomics, a web service created by developmental biologist Michele Markstein and computer scientist Ka-Ping Yee.
We would like to thank Peter Markstein and Vicky Markstein of in silico Labs for contributing the search engine algorithm. Server funding is provided by the UC Berkeley Center for Integrative Genomics.